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An Ensemble of Classifiers based Approach for Prediction of Alzheimer's Disease using fMRI Images based on Fusion of Volumetric, Textural and Hemodynamic FeaturesMALIK, F.   , FARHAN, S. , FAHIEM, M. A. |
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Author keywords
biomedical image processing, computer aided diagnosis, feature extraction, image classification, pattern recognition
References keywords
alzheimer(51), disease(38), imaging(12), functional(12), fmri(12), brain(11), diagnosis(10), dementia(8), classification(8), neuroimage(7)
Blue keywords are present in both the references section and the paper title.
About this article
Date of Publication: 2018-02-28
Volume 18, Issue 1, Year 2018, On page(s): 61 - 70
ISSN: 1582-7445, e-ISSN: 1844-7600
Digital Object Identifier: 10.4316/AECE.2018.01008
Web of Science Accession Number: 000426449500008
SCOPUS ID: 85043280771
Abstract
Alzheimer's is a neurodegenerative disease caused by the destruction and death of brain neurons resulting in memory loss, impaired thinking ability, and in certain behavioral changes. Alzheimer disease is a major cause of dementia and eventually death all around the world. Early diagnosis of the disease is crucial which can help the victims to maintain their level of independence for comparatively longer time and live a best life possible. For early detection of Alzheimer's disease, we are proposing a novel approach based on fusion of multiple types of features including hemodynamic, volumetric and textural features of the brain. Our approach uses non-invasive fMRI with ensemble of classifiers, for the classification of the normal controls and the Alzheimer patients. For performance evaluation, ten-fold cross validation is used. Individual feature sets and fusion of features have been investigated with ensemble classifiers for successful classification of Alzheimer's patients from normal controls. It is observed that fusion of features resulted in improved results for accuracy, specificity and sensitivity. |
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Stefan cel Mare University of Suceava, Romania
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Faculty of Electrical Engineering and Computer Science
Stefan cel Mare University of Suceava, Romania
All rights reserved: Advances in Electrical and Computer Engineering is a registered trademark of the Stefan cel Mare University of Suceava. No part of this publication may be reproduced, stored in a retrieval system, photocopied, recorded or archived, without the written permission from the Editor. When authors submit their papers for publication, they agree that the copyright for their article be transferred to the Faculty of Electrical Engineering and Computer Science, Stefan cel Mare University of Suceava, Romania, if and only if the articles are accepted for publication. The copyright covers the exclusive rights to reproduce and distribute the article, including reprints and translations.
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Disclaimer: Whilst every effort is made by the publishers and editorial board to see that no inaccurate or misleading data, opinions or statements appear in this journal, they wish to make it clear that all information and opinions formulated in the articles, as well as linguistic accuracy, are the sole responsibility of the author.